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Webinar Recap: Preventing Type 1 Diabetes
For a long time, doctors had to wait until someone got really sick before they could diagnose them with Type 1 Diabetes (T1D). By that time, the body had mostly stopped making insulin, and the patient had to start taking insulin shots right away. But today, we are entering a brand-new era. Scientists have figured...
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How Stem Cells Are Rewriting the Cure for Type 1 Diabetes
Type 1 diabetes develops when the body’s immune system mistakenly attacks its own beta cells – the cells in the pancreas that produce insulin. This means that any cure requires scientists to solve two problems. First, finding a reliable source of healthy beta cells so that they can be transplanted into an affected person. Second,...
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Where Do Transplanted Beta Cells Go In The Body?
Islet transplantation is an emerging therapy that aims to restore insulin-producing beta cells in people with type 1 diabetes (T1D). But an important question is: where in the body should these cells be placed? Transplantation sites can be broadly divided into two categories: intravascular (through blood vessels) and extravascular (into tissues outside the bloodstream). In...
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Why Is It So Hard To Keep Transplanted Beta Cells Alive?
Why are beta cells transplanted? Insulin-producing beta cells in the pancreas are critical for helping to keep blood sugar levels in a healthy range. Type I diabetes develops when these cells, found in cell clusters called islets, are attacked and destroyed by a person’s own immune system. Clinical trials have shown that it is possible...
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Why Can’t Everyone with Type 1 Diabetes Get an Islet Transplant?
Islet transplantation is an emerging therapy for type 1 diabetes (T1D) that aims to restore the body’s ability to make insulin. In this minimally invasive procedure, insulin-producing mini-organs (“islets”) are taken from a donor pancreas and delivered into the liver of a person with T1D. These islets then help stabilize blood sugar levels, reduce the...
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Are all β-cells destroyed in T1D?
The pancreas contains clusters of cells called islets. Insulin is produced by one of these cell types – the β-cell (or beta cell). As discussed in many other blogs, insulin is the only hormone that lowers blood glucose levels. In people with type 1 diabetes (T1D), the body’s immune system mistakenly attacks and destroys these...